disposable diaper to collect urine samples from young children for pyrethroid pesticide studies - polyacrylate

by:Demi     2019-09-01
disposable diaper to collect urine samples from young children for pyrethroid pesticide studies  -  polyacrylate
Disposable diapers are widely used in the United States and many other parts of the world;
Therefore, they are the ideal urine collection medium for measuring the exposure of young children to pesticides.
However, disposable diapers usually contain acrylic polymers, which makes it very difficult to extract and analyze urine.
The purpose of this paper is to evaluate whether disposable diapers containing acrylic particles can be extracted with salt solutions and whether they can be used to collect and quantitatively measure the selected urinary pseudo-Chrysanthemum pesticide metabolites and insides.
Storage Stability of metabolites and urea in wet diapers at body temperature and cold storage temperature was also evaluated.
The effects of saline solutions including Dishui calcium chloride, magnesium sulfate, ammonium acetate and sodium chloride solutions on the shrinkage efficiency of the polymer were tested.
Pesticide metabolites 3-(2,2-dichlorovinyl)-2,2-dimethyl-(1-cyclopropane)
Acid (DCCA), 3-(2,2-dibromovinyl)-2,2,dimethyl-(1-cyclopropane)
Acid (DBCA)and 3-
Benzene oxygen benzene acid (3-PBA)
The analysis was performed using LC/MS and the recovery rate of urine released by diapers was evaluated.
The study found that calcium chloride dihydate was satisfactory in releasing urine and metabolites from the polymer.
The recovery rate of the three tested pseudo-pesticide metabolites is mostly between 65-130.
The recovery rate of incoside is between 71-133.
The respective detection limit of the three metabolites is 0. 1u2009μg/l.
Quasi-Chrysanthemum glucose metabolites and urea on diapers are stable for at least 72 h.
We conclude from this study that calcium chloride dihydrate can successfully release urine and metabolites from propylene salts
Containing diapers, this method is expected to be used in the study of pesticide-like metabolites.
For large cohort studies involving young children wearing diapers, develop a convenient and low
Cost methods for collecting urine and analyzing urine metabolites.
Disposable diapers are widely used in the United States and many other parts of the world;
Therefore, they are the ideal medium for collecting urine.
However, disposable diapers usually contain polypropylene acid polymers, which makes it very difficult to extract and analyze urine.
In order to avoid the problem of extraction, we put gauze mats on diapers to collect urine samples ().
However, the problem with gauze method is that only 3-12 ml of urine can be expressed;
Produce up to 17 ml of urine from normal 1-3year-
Old children can be analyzed.
This volume limit of the gauze mat may affect the detection limit and the number of analyses for a given sample.
A typical commercial disposable diaper contains several parts: a suction pad made of polyacrylic resin absorbent powder mixed in fluffy wood cellulose fiber, a porous polypropylene top and back, two lateral tape front tape, elastic around the legs.
The suction pad with polyacrylic resin water absorption powder is the main part of collecting urine ().
Polyacrylic resin used in diapers is a class of polymers with extraordinary water absorption capacity.
Describes the water absorption process of sodium propylene ([CH–CH–(COONa)–])
It is one of the simplest polymers in commercial diapers.
The polymer chain is spiral when in a powder state.
When water comes, the sodium ions separate, making the amino group negatively charged and repelled against each other to unlock the polymer chain, allowing more water to bind to more amino or sodium atoms.
The polymer expands into a gel as it continues to unravel and absorb waterlike material.
Because the polymer also has weak cross
Link attribute, it effectively terrain into a three
Size structure ().
However, in the presence of some metal ions, the polymer will collapse or "shrink ".
The polymer chain fracture caused by Ca was demonstrated.
The ester base of the Ca ion binding polymer, neutralizes the Poly ion.
The acrylic chain breaks due to the hydrophobic properties of the trunk.
The combination of static and dynamic light scattering indicates the tight spherical shape of the folded polymer ().
This property of polymer shrinkage makes it possible to release urine metabolites from gel diapers again.
Most of the absorbed liquid is released once the polymer collapses, thus recovering the analytes.
It is a broad class of synthetic pesticides.
It is widely used in crops, garden plants, pets and spectral pesticides directly used in humans. By the mid-
Of the $1990 in global pesticide market value, the use of proposed pesticides has grown to $ 23%, ranking second only after organic phosphorus compounds ().
After the EPA banned indoor use of two of the most commonly used pesticides, chlorfos and nitrogen, the use of the proposed pesticides is increasing.
As a neurotoxin, chlorhexyl Ester acts on the sodium channel of the excited nerve ().
The most important process in pesticide metabolism is the cutting of the central ester bond that occurs in the liver ().
A list of mother-proposed pesticides and their corresponding metabolites widely used as exposure assessment biomarkers.
Metabolic products are mainly discharged from urine.
According to the survey, half of the pesticides
The lifetime of metabolites in the blood ranges from 7 to 55 u2009 h ().
In this paper, we have tried several salt solutions to destroy polymer gels in diapers.
The purpose of this paper is to evaluate whether disposable diapers containing polypropylene granules can be extracted using saline, and whether they can be used to collect and quantitatively measure selected urinary pseudo-Chrysanthemum pesticide metabolites and urea.
In addition, Storage Stability of pseudo-pesticide metabolites and urea in wet diapers was evaluated.
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